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    Welcome to Isle® Casino in historic Cape Girardeau, Missouri. We are a state of the art gaming and entertainment destination with all of the amenities and services you are looking for. Located in downtown Cape Girardeau, our casino features over 900 slots, 21 exciting table games, 7 live action poker tables, 5 restaurants, live entertainment and a breathtaking view of the Mississippi river.
  • Isle Casino Cape Girardeau 

    777 North Main St
    Cape Girardeau, MO 63701


    Isle Casino Cape Girardeau

    Open 24 hours on weekends
    Monday – Friday • closed from 4:00am – 8:00am

    SlotsIsle Casino offers an exciting gaming experience with over 900 of the hottest slots and featuring a wide variety of popular games.
    Table Games The casino also offers 21 table games including Roulette, Craps, and Blackjack as well as a 7-table poker room.
    Farmer's Pick BuffetAt Farmer’s Pick Buffet, we’ve partnered with local vendors to ensure our chefs have access to the freshest and highest quality ingredients. How do we know that? Because they came from just down the road! From the farm, to our kitchen, to your plate, every meal is pure satisfaction.
    Farraddays'From smoked St. Louis style ribs slathered in BBQ sauce to the 24 oz. porterhouse steak, meat lovers everywhere can rejoice at Farraddays. This classic American steakhouse is a taste of traditional, home-style cooking.
    Keller'sEnjoy the view overlooking the Mississippi River while you dine on savory small plates, specialty cocktails and seasonal beers. Named after the late Paul Keller, our newest restaurant gives diners a taste of local flavors served with a side of Southern Missouri hospitality.
    Lone Wolf ExpressIn a rush to grab a quick bite before hitting the casino floor? Lone Wolf Express has you covered with several grab n’ go options including: pre-made salads, sandwiches and desserts.
    The Lone Wolf

    When it’s time to unwind, join us at the Lone Wolf, where the only thing hotter than the wings is the entertainment. If you can pull yourself away from the dance floor, the Lone Wolf serves jumbo onion rings, fried pickles, pulled pork quesadillas and many more mouth-watering appetizers and entrées to compliment your drink of choice.